QuickView for Apolipoprotein D;jsessionid=2311AED6A988D9A8CB151650E97F713E;jsessionid=2EF85CA05785168009E8532AEF14195E (gene)

Gene Symbol:

Apod Mus musculus

Full name:

apolipoprotein D

Synonyms:

apolipoprotein D

Genomic Location:

Chr 16: 31296278-31314682

Description:

The protein encoded by this gene is a component of high-density lipoprotein (HDL), but is unique in that it shares greater structural similarity to lipocalin than to other members of the apolipoprotein family, and has a wider tissue expression pattern. The encoded protein is involved in lipid metabolism, and ablation of this gene results in defects...

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The protein encoded by this gene is a component of high-density lipoprotein (HDL), but is unique in that it shares greater structural similarity to lipocalin than to other members of the apolipoprotein family, and has a wider tissue expression pattern. The encoded protein is involved in lipid metabolism, and ablation of this gene results in defects in triglyceride metabolism. Elevated levels of this gene product have been observed in multiple tissues of Niemann-Pick disease mouse models, as well as in some tumors. Alternative splicing results in multiple transcript variants.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GGGYGTGNY_UNKNOWN ,  CAGCTG_AP4_Q5 ,  CTTTGT_LEF1_Q2 ,  TGGAAA_NFAT_Q4_01 ,  TATAAA_TATA_01

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